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Human-Relevant Sensitivity of iPSC-Derived Human Motor Neurons to BoNT/A1 and B1
The application of botulinum neurotoxins (BoNTs) for medical treatments necessitates a potency quantification of these lethal bacterial toxins, resulting in the use of a large number of test animals. Available alternative methods are limited in their relevance, as they are based on rodent cells or n...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402508/ https://www.ncbi.nlm.nih.gov/pubmed/34437455 http://dx.doi.org/10.3390/toxins13080585 |