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VENUS, a Novel Selection Approach to Improve the Accuracy of Neoantigens’ Prediction

Neoantigens are tumor-specific antigens able to induce T-cell responses, generated by mutations in protein-coding regions of expressed genes. Previous studies demonstrated that only a limited subset of mutations generates neoantigens in microsatellite stable tumors. We developed a method, called VEN...

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Detalles Bibliográficos
Autores principales: Leoni, Guido, D’Alise, Anna Morena, Tucci, Fabio Giovanni, Micarelli, Elisa, Garzia, Irene, De Lucia, Maria, Langone, Francesca, Nocchi, Linda, Cotugno, Gabriella, Bartolomeo, Rosa, Romano, Giuseppina, Allocca, Simona, Troise, Fulvia, Nicosia, Alfredo, Lahm, Armin, Scarselli, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402534/
https://www.ncbi.nlm.nih.gov/pubmed/34452005
http://dx.doi.org/10.3390/vaccines9080880