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VENUS, a Novel Selection Approach to Improve the Accuracy of Neoantigens’ Prediction
Neoantigens are tumor-specific antigens able to induce T-cell responses, generated by mutations in protein-coding regions of expressed genes. Previous studies demonstrated that only a limited subset of mutations generates neoantigens in microsatellite stable tumors. We developed a method, called VEN...
Autores principales: | Leoni, Guido, D’Alise, Anna Morena, Tucci, Fabio Giovanni, Micarelli, Elisa, Garzia, Irene, De Lucia, Maria, Langone, Francesca, Nocchi, Linda, Cotugno, Gabriella, Bartolomeo, Rosa, Romano, Giuseppina, Allocca, Simona, Troise, Fulvia, Nicosia, Alfredo, Lahm, Armin, Scarselli, Elisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402534/ https://www.ncbi.nlm.nih.gov/pubmed/34452005 http://dx.doi.org/10.3390/vaccines9080880 |
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