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In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei

Murine dendritic cells, when pulsed with heat-killed Burkholderia pseudomallei and used to immunise naïve mice, have previously been shown to induce protective immunity in vivo. We have now demonstrated the in vitro priming of naïve human T cells against heat-killed B. pseudomallei, by co-culture wi...

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Detalles Bibliográficos
Autores principales: Reddi, Durga, Durant, Lydia, Bernardo, David, Noble, Alistair, English, Nicholas R., Hendy, Philip, Clark, Graeme C., Prior, Joann L., Williamson, Ethel Diane, Knight, Stella C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402564/
https://www.ncbi.nlm.nih.gov/pubmed/34452057
http://dx.doi.org/10.3390/vaccines9080929