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Islatravir Is Not Expected to Be a Victim or Perpetrator of Drug-Drug Interactions via Major Drug-Metabolizing Enzymes or Transporters

Islatravir (MK-8591) is a nucleoside reverse transcriptase translocation inhibitor in development for the treatment and prevention of HIV-1. The potential for islatravir to interact with commonly co-prescribed medications was studied in vitro. Elimination of islatravir is expected to be balanced bet...

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Detalles Bibliográficos
Autores principales: Bleasby, Kelly, Houle, Robert, Hafey, Michael, Lin, Meihong, Guo, Jingjing, Lu, Bing, Sanchez, Rosa I., Fillgrove, Kerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402619/
https://www.ncbi.nlm.nih.gov/pubmed/34452431
http://dx.doi.org/10.3390/v13081566