A Genome-Wide CRISPR/Cas9 Screen Reveals the Requirement of Host Sphingomyelin Synthase 1 for Infection with Pseudorabies Virus Mutant gD(–)Pass

Herpesviruses are large DNA viruses, which encode up to 300 different proteins including enzymes enabling efficient replication. Nevertheless, they depend on a multitude of host cell proteins for successful propagation. To uncover cellular host factors important for replication of pseudorabies virus...

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Detalles Bibliográficos
Autores principales: Hölper, Julia E., Grey, Finn, Baillie, John Kenneth, Regan, Tim, Parkinson, Nicholas J., Höper, Dirk, Thamamongood, Thiprampai, Schwemmle, Martin, Pannhorst, Katrin, Wendt, Lisa, Mettenleiter, Thomas C., Klupp, Barbara G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402627/
https://www.ncbi.nlm.nih.gov/pubmed/34452438
http://dx.doi.org/10.3390/v13081574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402627/
https://www.ncbi.nlm.nih.gov/pubmed/34452438
http://dx.doi.org/10.3390/v13081574

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