A Fully Protective Congenital CMV Vaccine Requires Neutralizing Antibodies to Viral Pentamer and gB Glycoprotein Complexes but a pp65 T-Cell Response Is Not Necessary

A vaccine against congenital cytomegalovirus infection is a high priority. Guinea pig cytomegalovirus (GPCMV) is the only congenital CMV small animal model. GPCMV encodes essential glycoprotein complexes for virus entry (gB, gH/gL/gO, gM/gN) including a pentamer complex (gH/gL/GP129/GP131/GP133 or P...

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Detalles Bibliográficos
Autores principales: Choi, K. Yeon, McGregor, Alistair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402731/
https://www.ncbi.nlm.nih.gov/pubmed/34452332
http://dx.doi.org/10.3390/v13081467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402731/
https://www.ncbi.nlm.nih.gov/pubmed/34452332
http://dx.doi.org/10.3390/v13081467

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