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Lentiviral Vectors for T Cell Engineering: Clinical Applications, Bioprocessing and Future Perspectives

Lentiviral vectors have played a critical role in the emergence of gene-modified cell therapies, specifically T cell therapies. Tisagenlecleucel (Kymriah), axicabtagene ciloleucel (Yescarta) and most recently brexucabtagene autoleucel (Tecartus) are examples of T cell therapies which are now commerc...

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Detalles Bibliográficos
Autores principales: Labbé, Roman P., Vessillier, Sandrine, Rafiq, Qasim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402758/
https://www.ncbi.nlm.nih.gov/pubmed/34452392
http://dx.doi.org/10.3390/v13081528