Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease

Pathogenic New World orthohantaviruses cause hantavirus cardiopulmonary syndrome (HCPS), a severe immunopathogenic disease in humans manifested by pulmonary edema and respiratory distress, with case fatality rates approaching 40%. High levels of inflammatory mediators are present in the lungs and sy...

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Detalles Bibliográficos
Autores principales: Simons, Peter, Guo, Yan, Bondu, Virginie, Tigert, Susan L., Harkins, Michelle, Goodfellow, Samuel, Tompkins, Cana, Chabot-Richards, Devon, Yang, Xuexian O., Bosc, Laura Gonzalez, Bradfute, Steven, Lawrence, Daniel A., Buranda, Tione
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402847/
https://www.ncbi.nlm.nih.gov/pubmed/34452463
http://dx.doi.org/10.3390/v13081597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402847/
https://www.ncbi.nlm.nih.gov/pubmed/34452463
http://dx.doi.org/10.3390/v13081597

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