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Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease

Pathogenic New World orthohantaviruses cause hantavirus cardiopulmonary syndrome (HCPS), a severe immunopathogenic disease in humans manifested by pulmonary edema and respiratory distress, with case fatality rates approaching 40%. High levels of inflammatory mediators are present in the lungs and sy...

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Detalles Bibliográficos
Autores principales:	Simons, Peter, Guo, Yan, Bondu, Virginie, Tigert, Susan L., Harkins, Michelle, Goodfellow, Samuel, Tompkins, Cana, Chabot-Richards, Devon, Yang, Xuexian O., Bosc, Laura Gonzalez, Bradfute, Steven, Lawrence, Daniel A., Buranda, Tione
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402847/ https://www.ncbi.nlm.nih.gov/pubmed/34452463 http://dx.doi.org/10.3390/v13081597

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