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Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved

Statin derivatives can inhibit the replication of a range of viruses, including hepatitis C virus (HCV, Hepacivirus), dengue virus (Flavivirus), African swine fever virus (Asfarviridae) and poliovirus (Picornaviridae). We assess the antiviral effect of fluvastatin in cells infected with orbiviruses...

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Detalles Bibliográficos
Autores principales: Mohd Jaafar, Fauziah, Monsion, Baptiste, Belhouchet, Mourad, Mertens, Peter P. C., Attoui, Houssam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402872/
https://www.ncbi.nlm.nih.gov/pubmed/34452303
http://dx.doi.org/10.3390/v13081437