A Gut Reaction to SIV and SHIV Infection: Lower Dysregulation of Mucosal T Cells during Acute Infection Is Associated with Greater Viral Suppression during cART

Selection of a pre-clinical non-human primate (NHP) model is essential when evaluating therapeutic vaccine and treatment strategies for HIV. SIV and SHIV-infected NHPs exhibit a range of viral burdens, pathologies, and responses to combinatorial antiretroviral therapy (cART) regimens and the choice...

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Detalles Bibliográficos
Autores principales: O’Connor, Megan A., Munson, Paul V., Dross, Sandra E., Tunggal, Hillary C., Lewis, Thomas B., Osborn, Jessica, Peterson, Christopher W., Huang, Meei-Li W., Moats, Cassandra, Smedley, Jeremy, Jerome, Keith R., Kiem, Hans-Peter, Bagley, Kenneth C., Mullins, James I., Fuller, Deborah Heydenburg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402906/
https://www.ncbi.nlm.nih.gov/pubmed/34452474
http://dx.doi.org/10.3390/v13081609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402906/
https://www.ncbi.nlm.nih.gov/pubmed/34452474
http://dx.doi.org/10.3390/v13081609

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