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A Gut Reaction to SIV and SHIV Infection: Lower Dysregulation of Mucosal T Cells during Acute Infection Is Associated with Greater Viral Suppression during cART
Selection of a pre-clinical non-human primate (NHP) model is essential when evaluating therapeutic vaccine and treatment strategies for HIV. SIV and SHIV-infected NHPs exhibit a range of viral burdens, pathologies, and responses to combinatorial antiretroviral therapy (cART) regimens and the choice...
Autores principales: | O’Connor, Megan A., Munson, Paul V., Dross, Sandra E., Tunggal, Hillary C., Lewis, Thomas B., Osborn, Jessica, Peterson, Christopher W., Huang, Meei-Li W., Moats, Cassandra, Smedley, Jeremy, Jerome, Keith R., Kiem, Hans-Peter, Bagley, Kenneth C., Mullins, James I., Fuller, Deborah Heydenburg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402906/ https://www.ncbi.nlm.nih.gov/pubmed/34452474 http://dx.doi.org/10.3390/v13081609 |
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