Magnesium Hydroxide Nanoparticles Improve the Ocular Hypotensive Effect of Twice Daily Topical Timolol Maleate in Healthy Dogs

Timolol maleate (TM), a beta-adrenergic receptor antagonist, is widely used for canine antiglaucoma eye drops; however, its bioavailability is <5%. Our previous study revealed that magnesium hydroxide nanoparticles (nMH) have potency in improving the bioavailability of fixed-combined TM in rodent...

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Detalles Bibliográficos
Autores principales: Kita, Mizuki, Kanai, Kazutaka, Mitsuhashi, Hiroki, Noguchi, Tomoki, Nagai, Noriaki, Yamaguchi, Mizuki, Otaka, Yuya, Kudo, Rina, Yamashita, Yohei, Tajima, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402916/
https://www.ncbi.nlm.nih.gov/pubmed/34437490
http://dx.doi.org/10.3390/vetsci8080168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402916/
https://www.ncbi.nlm.nih.gov/pubmed/34437490
http://dx.doi.org/10.3390/vetsci8080168

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