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Protective Effects of Astodrimer Sodium 1% Nasal Spray Formulation against SARS-CoV-2 Nasal Challenge in K18-hACE2 Mice

Strategies to combat COVID-19 require multiple ways to protect vulnerable people from infection. SARS-CoV-2 is an airborne pathogen and the nasal cavity is a primary target of infection. The K18-hACE2 mouse model was used to investigate the anti-SARS-CoV-2 efficacy of astodrimer sodium formulated in...

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Detalles Bibliográficos
Autores principales: Paull, Jeremy R. A., Luscombe, Carolyn A., Castellarnau, Alex, Heery, Graham P., Bobardt, Michael D., Gallay, Philippe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402925/
https://www.ncbi.nlm.nih.gov/pubmed/34452519
http://dx.doi.org/10.3390/v13081656