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Inhibition of ADAM10 ameliorates doxorubicin-induced cardiac remodeling by suppressing N-cadherin cleavage

The present research was designed to examine the effects of disintegrin metalloproteinases 10 (ADAM10) on the doxorubicin (DOX)-induced dilated cardiomyopathy (DCM) and the mechanisms involved, with a focus on ADAM10-dependent cleavage of N-cadherin. The present study constructed recombinant lentivi...

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Detalles Bibliográficos
Autores principales: Li, Xiaoou, Pan, Feng, He, Bing, Fang, Chengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402944/
https://www.ncbi.nlm.nih.gov/pubmed/34522779
http://dx.doi.org/10.1515/biol-2021-0081