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Anti-Integrins for the Treatment of Inflammatory Bowel Disease: Current Evidence and Perspectives

Leukocyte trafficking to the gastrointestinal tract is recognized to play a role in the pathogenesis of inflammatory bowel disease (IBD). Integrins are expressed on immune cells and interact with cell adhesion molecules (CAM) to mediate leukocyte trafficking. Blockade of the gut-tropic integrin α4β7...

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Detalles Bibliográficos
Autores principales: Gubatan, John, Keyashian, Kian, Rubin, Samuel J S, Wang, Jenny, Buckman, Cyrus A, Sinha, Sidhartha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402953/
https://www.ncbi.nlm.nih.gov/pubmed/34466013
http://dx.doi.org/10.2147/CEG.S293272