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Anti-Integrins for the Treatment of Inflammatory Bowel Disease: Current Evidence and Perspectives
Leukocyte trafficking to the gastrointestinal tract is recognized to play a role in the pathogenesis of inflammatory bowel disease (IBD). Integrins are expressed on immune cells and interact with cell adhesion molecules (CAM) to mediate leukocyte trafficking. Blockade of the gut-tropic integrin α4β7...
Autores principales: | Gubatan, John, Keyashian, Kian, Rubin, Samuel J S, Wang, Jenny, Buckman, Cyrus A, Sinha, Sidhartha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402953/ https://www.ncbi.nlm.nih.gov/pubmed/34466013 http://dx.doi.org/10.2147/CEG.S293272 |
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