Comparison of Three Different Aqueous Microenvironments for Enhancing Oral Bioavailability of Sildenafil: Solid Self-Nanoemulsifying Drug Delivery System, Amorphous Microspheres and Crystalline Microspheres

BACKGROUND: The purpose of this study was to screen various drug delivery systems for improving the aqueous solubility and oral bioavailability of sildenafil. Three representative techniques, solid self-nanoemulsifying drug delivery systems (SNEDDS), amorphous microspheres and crystalline microspher...

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Detalles Bibliográficos
Autores principales: Kim, Jung Suk, Din, Fakhar ud, Lee, Sang Min, Kim, Dong Shik, Woo, Mi Ran, Cheon, Seunghyun, Ji, Sang Hun, Kim, Jong Oh, Youn, Yu Seok, Oh, Kyung Taek, Lim, Soo-Jeong, Jin, Sung Giu, Choi, Han-Gon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402991/
https://www.ncbi.nlm.nih.gov/pubmed/34465992
http://dx.doi.org/10.2147/IJN.S324206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402991/
https://www.ncbi.nlm.nih.gov/pubmed/34465992
http://dx.doi.org/10.2147/IJN.S324206

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