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Comparison of Three Different Aqueous Microenvironments for Enhancing Oral Bioavailability of Sildenafil: Solid Self-Nanoemulsifying Drug Delivery System, Amorphous Microspheres and Crystalline Microspheres
BACKGROUND: The purpose of this study was to screen various drug delivery systems for improving the aqueous solubility and oral bioavailability of sildenafil. Three representative techniques, solid self-nanoemulsifying drug delivery systems (SNEDDS), amorphous microspheres and crystalline microspher...
Autores principales: | Kim, Jung Suk, Din, Fakhar ud, Lee, Sang Min, Kim, Dong Shik, Woo, Mi Ran, Cheon, Seunghyun, Ji, Sang Hun, Kim, Jong Oh, Youn, Yu Seok, Oh, Kyung Taek, Lim, Soo-Jeong, Jin, Sung Giu, Choi, Han-Gon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402991/ https://www.ncbi.nlm.nih.gov/pubmed/34465992 http://dx.doi.org/10.2147/IJN.S324206 |
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