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A Multicenter, Double-Blind, Randomized, Placebo-Controlled Phase 2b Trial of Cytisinicline in Adult Smokers (The ORCA-1 Trial)

INTRODUCTION: Cytisinicline (known as cytisine), a nicotinic acetylcholine receptor partial agonist, is a smoking cessation aid currently marketed in Central and Eastern Europe using a 1.5-mg/tablet 25-day downward titration schedule. No prior studies have evaluated other doses or administration sch...

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Detalles Bibliográficos
Autores principales: Nides, Mitchell, Rigotti, Nancy A, Benowitz, Neal, Clarke, Anthony, Jacobs, Cindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403245/
https://www.ncbi.nlm.nih.gov/pubmed/33847362
http://dx.doi.org/10.1093/ntr/ntab073