Inactivation of Interleukin‐4 Receptor α Signaling in Myeloid Cells Protects Mice From Angiotensin II/High Salt–Induced Cardiovascular Dysfunction Through Suppression of Fibrotic Remodeling

BACKGROUND: Hypertension‐induced cardiovascular remodeling is characterized by chronic low‐grade inflammation. Interleukin‐4 receptor α (IL‐4Rα) signaling is importantly involved in cardiovascular remodeling, however, the target cell type(s) is unclear. Here, we investigated the role of myeloid‐spec...

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Detalles Bibliográficos
Autores principales: Song, Jianrui, Frieler, Ryan A., Vigil, Thomas M., Ma, Jun, Brombacher, Frank, Goonewardena, Sascha N., Goldstein, Daniel R., Mortensen, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403318/
https://www.ncbi.nlm.nih.gov/pubmed/34132103
http://dx.doi.org/10.1161/JAHA.120.017329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403318/
https://www.ncbi.nlm.nih.gov/pubmed/34132103
http://dx.doi.org/10.1161/JAHA.120.017329

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