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Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies

Synucleinopathies, including Parkinson’s disease (PD), Lewy body dementia (LBD), Alzheimer’s disease with amygdala restricted Lewy bodies (AD/ALB), and multiple system atrophy (MSA) comprise a spectrum of neurodegenerative disorders characterized by the presence of distinct pathological α-synuclein...

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Detalles Bibliográficos
Autores principales: Hass, Ethan W., Sorrentino, Zachary A., Xia, Yuxing, Lloyd, Grace M., Trojanowski, John Q., Prokop, Stefan, Giasson, Benoit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403399/
https://www.ncbi.nlm.nih.gov/pubmed/34454615
http://dx.doi.org/10.1186/s40478-021-01242-2