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Derivation and characterization of an HIV-1 mutant that rescues IP(6) binding deficiency
BACKGROUND: A critical step in the HIV-1 replication cycle is the assembly of Gag proteins to form virions at the plasma membrane. Virion assembly and maturation are facilitated by the cellular polyanion inositol hexaphosphate (IP(6)), which is proposed to stabilize both the immature Gag lattice and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403458/ https://www.ncbi.nlm.nih.gov/pubmed/34454514 http://dx.doi.org/10.1186/s12977-021-00571-3 |