Anti-high mobility group box 1 monoclonal antibody suppressed hyper-permeability and cytokine production in human pulmonary endothelial cells infected with influenza A virus

OBJECTIVE: High mobility group box-1 (HMGB1) has been reported to be involved in influenza A virus-induced acute respiratory distress syndrome (ARDS). We studied the efficacy of an anti-HMGB1 mAb using an in vitro model of TNF-α stimulation or influenza A virus infection in human pulmonary microvasc...

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Detalles Bibliográficos
Autores principales: Namba, Takahiro, Tsuge, Mitsuru, Yashiro, Masato, Saito, Yukie, Liu, Keyue, Nishibori, Masahiro, Morishima, Tsuneo, Tsukahara, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403468/
https://www.ncbi.nlm.nih.gov/pubmed/34455489
http://dx.doi.org/10.1007/s00011-021-01496-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403468/
https://www.ncbi.nlm.nih.gov/pubmed/34455489
http://dx.doi.org/10.1007/s00011-021-01496-5

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