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Anti-high mobility group box 1 monoclonal antibody suppressed hyper-permeability and cytokine production in human pulmonary endothelial cells infected with influenza A virus

OBJECTIVE: High mobility group box-1 (HMGB1) has been reported to be involved in influenza A virus-induced acute respiratory distress syndrome (ARDS). We studied the efficacy of an anti-HMGB1 mAb using an in vitro model of TNF-α stimulation or influenza A virus infection in human pulmonary microvasc...

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Detalles Bibliográficos
Autores principales:	Namba, Takahiro, Tsuge, Mitsuru, Yashiro, Masato, Saito, Yukie, Liu, Keyue, Nishibori, Masahiro, Morishima, Tsuneo, Tsukahara, Hirokazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403468/ https://www.ncbi.nlm.nih.gov/pubmed/34455489 http://dx.doi.org/10.1007/s00011-021-01496-5

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