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SOCS, SPRED, and NR4a: Negative regulators of cytokine signaling and transcription in immune tolerance
Cytokines are important intercellular communication tools for immunity. Most cytokines utilize the JAK-STAT and Ras-ERK pathways to promote gene transcription and proliferation; however, this signaling is tightly regulated. The suppressor of cytokine signaling (SOCS) family and SPRED family are a re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Academy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403526/ https://www.ncbi.nlm.nih.gov/pubmed/34121041 http://dx.doi.org/10.2183/pjab.97.016 |