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SOCS, SPRED, and NR4a: Negative regulators of cytokine signaling and transcription in immune tolerance

Cytokines are important intercellular communication tools for immunity. Most cytokines utilize the JAK-STAT and Ras-ERK pathways to promote gene transcription and proliferation; however, this signaling is tightly regulated. The suppressor of cytokine signaling (SOCS) family and SPRED family are a re...

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Detalles Bibliográficos
Autores principales: YOSHIMURA, Akihiko, AKI, Daisuke, ITO, Minako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403526/
https://www.ncbi.nlm.nih.gov/pubmed/34121041
http://dx.doi.org/10.2183/pjab.97.016