Preclinical model of type 1 diabetes and myocardial ischemia/reperfusion injury in conscious rabbits—demonstration of cardioprotection with rapamycin

We developed a preclinical model of myocardial ischemia/reperfusion (I/R) injury in conscious diabetic rabbits to identify an early pharmacological intervention for patients with diabetes and acute myocardial infarction (AMI). Here, we describe a reproducible protocol for induction of diabetes with...

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Detalles Bibliográficos
Autores principales: Samidurai, Arun, Ockaili, Ramzi, Cain, Chad, Roh, Sean K., Filippone, Scott M., Kraskauskas, Donatas, Kukreja, Rakesh C., Das, Anindita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403684/
https://www.ncbi.nlm.nih.gov/pubmed/34485939
http://dx.doi.org/10.1016/j.xpro.2021.100772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403684/
https://www.ncbi.nlm.nih.gov/pubmed/34485939
http://dx.doi.org/10.1016/j.xpro.2021.100772

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