Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor T cells in rhesus macaques

Chimeric antigen receptor (CAR) T cell therapies are being investigated as potential HIV cures and designed to target HIV reservoirs. Monoclonal antibodies (mAbs) targeting the simian immunodeficiency virus (SIV) envelope allowed us to investigate the potency of single-chain variable fragment (scFv)...

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Detalles Bibliográficos
Autores principales: Haeseleer, Françoise, Fukazawa, Yoshinori, Park, Haesun, Varco-Merth, Benjamin, Rust, Blake J., Smedley, Jeremy V., Eichholz, Karsten, Peterson, Christopher W., Mason, Rosemarie, Kiem, Hans-Peter, Roederer, Mario, Picker, Louis J., Okoye, Afam A., Corey, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403686/
https://www.ncbi.nlm.nih.gov/pubmed/34485613
http://dx.doi.org/10.1016/j.omtm.2021.06.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403686/
https://www.ncbi.nlm.nih.gov/pubmed/34485613
http://dx.doi.org/10.1016/j.omtm.2021.06.008

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