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Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor T cells in rhesus macaques
Chimeric antigen receptor (CAR) T cell therapies are being investigated as potential HIV cures and designed to target HIV reservoirs. Monoclonal antibodies (mAbs) targeting the simian immunodeficiency virus (SIV) envelope allowed us to investigate the potency of single-chain variable fragment (scFv)...
Autores principales: | Haeseleer, Françoise, Fukazawa, Yoshinori, Park, Haesun, Varco-Merth, Benjamin, Rust, Blake J., Smedley, Jeremy V., Eichholz, Karsten, Peterson, Christopher W., Mason, Rosemarie, Kiem, Hans-Peter, Roederer, Mario, Picker, Louis J., Okoye, Afam A., Corey, Lawrence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403686/ https://www.ncbi.nlm.nih.gov/pubmed/34485613 http://dx.doi.org/10.1016/j.omtm.2021.06.008 |
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