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CD133 mRNA-transfected dendritic cells induce coordinated cytotoxic and helper T cell responses against breast cancer stem cells

Breast cancer, a leading cause of death yearly, has been shown to be initiated and propagated by cancer stem cells. CD133, a cell surface antigen, has been shown to be present on cancer stem cells of many solid tumors, including breast cancer. A limitation to targeting CD133 is major histocompatibil...

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Detalles Bibliográficos
Autores principales: Tay, Angelique Sao-Mai Sy, Amano, Takayuki, Edwards, Lincoln A., Yu, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403713/
https://www.ncbi.nlm.nih.gov/pubmed/34485687
http://dx.doi.org/10.1016/j.omto.2021.05.006