Widespread ribosome stalling in a genome-reduced bacterium and the need for translational quality control

Trans-translation is a ubiquitous bacterial mechanism of ribosome rescue mediated by a transfer-messenger RNA (tmRNA) that adds a degradation tag to the truncated nascent polypeptide. Here, we characterize this quality control system in a genome-reduced bacterium, Mycoplasma pneumoniae (MPN), and pe...

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Detalles Bibliográficos
Autores principales: Burgos, Raul, Weber, Marc, Gallo, Carolina, Lluch-Senar, Maria, Serrano, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403727/
https://www.ncbi.nlm.nih.gov/pubmed/34485867
http://dx.doi.org/10.1016/j.isci.2021.102985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403727/
https://www.ncbi.nlm.nih.gov/pubmed/34485867
http://dx.doi.org/10.1016/j.isci.2021.102985

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