Loss of synergistic transcriptional feedback loops drives diverse B-cell cancers

BACKGROUND: The most common B-cell cancers, chronic lymphocytic leukemia/lymphoma (CLL), follicular and diffuse large B-cell (FL, DLBCL) lymphomas, have distinct clinical courses, yet overlapping “cell-of-origin”. Dynamic changes to the epigenome are essential regulators of B-cell differentiation. T...

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Detalles Bibliográficos
Autores principales: Andrews, Jared M., Pyfrom, Sarah C., Schmidt, Jennifer A., Koues, Olivia I., Kowalewski, Rodney A., Grams, Nicholas R., Sun, Jessica J., Berman, Leigh R., Duncavage, Eric J., Lee, Yi-Shan, Cashen, Amanda F., Oltz, Eugene M., Payton, Jacqueline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403728/
https://www.ncbi.nlm.nih.gov/pubmed/34461601
http://dx.doi.org/10.1016/j.ebiom.2021.103559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403728/
https://www.ncbi.nlm.nih.gov/pubmed/34461601
http://dx.doi.org/10.1016/j.ebiom.2021.103559

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