Molecular basis of cholesterol efflux via ABCG subfamily transporters

The ABCG1 homodimer (G1) and ABCG5–ABCG8 heterodimer (G5G8), two members of the adenosine triphosphate (ATP)–binding cassette (ABC) transporter G family, are required for maintenance of cellular cholesterol levels. G5G8 mediates secretion of neutral sterols into bile and the gut lumen, whereas G1 tr...

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Detalles Bibliográficos
Autores principales: Sun, Yingyuan, Wang, Jin, Long, Tao, Qi, Xiaofeng, Donnelly, Linda, Elghobashi-Meinhardt, Nadia, Esparza, Leticia, Cohen, Jonathan C., Xie, Xiao-Song, Hobbs, Helen H., Li, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403869/
https://www.ncbi.nlm.nih.gov/pubmed/34404721
http://dx.doi.org/10.1073/pnas.2110483118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403869/
https://www.ncbi.nlm.nih.gov/pubmed/34404721
http://dx.doi.org/10.1073/pnas.2110483118

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