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Molecular basis of cholesterol efflux via ABCG subfamily transporters
The ABCG1 homodimer (G1) and ABCG5–ABCG8 heterodimer (G5G8), two members of the adenosine triphosphate (ATP)–binding cassette (ABC) transporter G family, are required for maintenance of cellular cholesterol levels. G5G8 mediates secretion of neutral sterols into bile and the gut lumen, whereas G1 tr...
Autores principales: | Sun, Yingyuan, Wang, Jin, Long, Tao, Qi, Xiaofeng, Donnelly, Linda, Elghobashi-Meinhardt, Nadia, Esparza, Leticia, Cohen, Jonathan C., Xie, Xiao-Song, Hobbs, Helen H., Li, Xiaochun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403869/ https://www.ncbi.nlm.nih.gov/pubmed/34404721 http://dx.doi.org/10.1073/pnas.2110483118 |
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