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Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2

Atomic structures of several proteins from the coronavirus family are still partial or unavailable. A possible reason for this gap is the instability of these proteins outside of the cellular context, thereby prompting the use of in-cell approaches. In situ cross-linking and mass spectrometry (in si...

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Detalles Bibliográficos
Autores principales: Slavin, Moriya, Zamel, Joanna, Zohar, Keren, Eliyahu, Tsiona, Braitbard, Merav, Brielle, Esther, Baraz, Leah, Stolovich-Rain, Miri, Friedman, Ahuva, Wolf, Dana G., Rouvinski, Alexander, Linial, Michal, Schneidman-Duhovny, Dina, Kalisman, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403911/
https://www.ncbi.nlm.nih.gov/pubmed/34373319
http://dx.doi.org/10.1073/pnas.2103554118