Rapid and dramatic responses to dabrafenib and trametinib in BRAF V600E‐mutated lung adenocarcinoma

V‐raf murine sarcoma viral oncogene homologue B1 (BRAF) is a proto‐oncogene that regulates cell proliferation and survival. BRAF V600E‐mutated lung cancer has aggressive characteristics and is resistant to chemotherapies. Combination of BRAF‐specific inhibitor dabrafenib and mitogen‐activated protei...

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Detalles Bibliográficos
Autores principales: Ota, Takayo, Okabayashi, Aya, Fukuoka, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403980/
https://www.ncbi.nlm.nih.gov/pubmed/34484797
http://dx.doi.org/10.1002/rcr2.841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403980/
https://www.ncbi.nlm.nih.gov/pubmed/34484797
http://dx.doi.org/10.1002/rcr2.841

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