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Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane
The Sonic hedgehog (Shh) pathway controls embryonic development and tissue homeostasis after birth. Long-standing questions about this pathway include how the dual-lipidated, firmly plasma membrane-associated Shh ligand is released from producing cells to signal to distant target cells and how the r...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403983/ https://www.ncbi.nlm.nih.gov/pubmed/34308968 http://dx.doi.org/10.1242/jcs.258672 |