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Tumour cell CD99 regulates transendothelial migration via CDC42 and actin remodelling

Metastasis requires tumour cells to cross endothelial cell (EC) barriers using pathways similar to those used by leucocytes during inflammation. Cell surface CD99 is expressed by healthy leucocytes and ECs, and participates in inflammatory transendothelial migration (TEM). Tumour cells also express...

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Detalles Bibliográficos
Autores principales: Mannion, Aarren J., Odell, Adam F., Taylor, Alison, Jones, Pamela F., Cook, Graham P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403985/
https://www.ncbi.nlm.nih.gov/pubmed/34374417
http://dx.doi.org/10.1242/jcs.240135