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The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach

The ability to design stable proteins with custom-made functions is a major goal in biochemistry with practical relevance for our environment and society. Understanding and manipulating protein stability provide crucial information on the molecular determinants that modulate structure and stability,...

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Detalles Bibliográficos
Autores principales: Romero-Romero, Sergio, Costas, Miguel, Silva Manzano, Daniel-Adriano, Kordes, Sina, Rojas-Ortega, Erendira, Tapia, Cinthya, Guerra, Yasel, Shanmugaratnam, Sooruban, Rodríguez-Romero, Adela, Baker, David, Höcker, Birte, Fernández-Velasco, D. Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404036/
https://www.ncbi.nlm.nih.gov/pubmed/34271011
http://dx.doi.org/10.1016/j.jmb.2021.167153