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The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach
The ability to design stable proteins with custom-made functions is a major goal in biochemistry with practical relevance for our environment and society. Understanding and manipulating protein stability provide crucial information on the molecular determinants that modulate structure and stability,...
Autores principales: | Romero-Romero, Sergio, Costas, Miguel, Silva Manzano, Daniel-Adriano, Kordes, Sina, Rojas-Ortega, Erendira, Tapia, Cinthya, Guerra, Yasel, Shanmugaratnam, Sooruban, Rodríguez-Romero, Adela, Baker, David, Höcker, Birte, Fernández-Velasco, D. Alejandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404036/ https://www.ncbi.nlm.nih.gov/pubmed/34271011 http://dx.doi.org/10.1016/j.jmb.2021.167153 |
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