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A high‐throughput predictive method for sequence‐similar fold switchers

Although most experimentally characterized proteins with similar sequences assume the same folds and perform similar functions, an increasing number of exceptions is emerging. One class of exceptions comprises sequence‐similar fold switchers, whose secondary structures shift from α‐helix <‐> β...

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Detalles Bibliográficos
Autores principales: Kim, Allen K., Looger, Loren L., Porter, Lauren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404102/
https://www.ncbi.nlm.nih.gov/pubmed/33462801
http://dx.doi.org/10.1002/bip.23416