Polycomb Repressive Complex 2 Modulation through the Development of EZH2–EED Interaction Inhibitors and EED Binders

[Image: see text] Epigenetics is nowadays a well-accepted area of research. In the last years, tremendous progress was made regarding molecules targeting EZH2, directly or indirectly. Recently tazemetostat hit the market after FDA-approval for the treatment of lymphoma. However, the impairment of EZ...

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Detalles Bibliográficos
Autores principales: Tomassi, Stefano, Romanelli, Annalisa, Zwergel, Clemens, Valente, Sergio, Mai, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404197/
https://www.ncbi.nlm.nih.gov/pubmed/34351144
http://dx.doi.org/10.1021/acs.jmedchem.1c00226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404197/
https://www.ncbi.nlm.nih.gov/pubmed/34351144
http://dx.doi.org/10.1021/acs.jmedchem.1c00226

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