Structure–Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands

[Image: see text] Chemotherapy with platinum complexes is essential for clinical anticancer therapy. However, due to side effects and drug resistance, further drug improvement is urgently needed. Herein, we report on triple-action platinum(IV) prodrugs, which, in addition to tumor targeting via male...

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Detalles Bibliográficos
Autores principales: Fronik, Philipp, Poetsch, Isabella, Kastner, Alexander, Mendrina, Theresa, Hager, Sonja, Hohenwallner, Katharina, Schueffl, Hemma, Herndler-Brandstetter, Dietmar, Koellensperger, Gunda, Rampler, Evelyn, Kopecka, Joanna, Riganti, Chiara, Berger, Walter, Keppler, Bernhard K., Heffeter, Petra, Kowol, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404199/
https://www.ncbi.nlm.nih.gov/pubmed/34403254
http://dx.doi.org/10.1021/acs.jmedchem.1c00770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404199/
https://www.ncbi.nlm.nih.gov/pubmed/34403254
http://dx.doi.org/10.1021/acs.jmedchem.1c00770

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