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A synaptic locus for TrkB signaling underlying ketamine rapid antidepressant action

Ketamine produces rapid antidepressant action in patients with major depression or treatment-resistant depression. Studies have identified brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin receptor kinase B (TrkB), as necessary for the antidepressant effects and underlying ketam...

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Detalles Bibliográficos
Autores principales: Lin, Pei-Yi, Ma, Z. Zack, Mahgoub, Melissa, Kavalali, Ege T., Monteggia, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404212/
https://www.ncbi.nlm.nih.gov/pubmed/34407417
http://dx.doi.org/10.1016/j.celrep.2021.109513