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A synaptic locus for TrkB signaling underlying ketamine rapid antidepressant action
Ketamine produces rapid antidepressant action in patients with major depression or treatment-resistant depression. Studies have identified brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin receptor kinase B (TrkB), as necessary for the antidepressant effects and underlying ketam...
Autores principales: | Lin, Pei-Yi, Ma, Z. Zack, Mahgoub, Melissa, Kavalali, Ege T., Monteggia, Lisa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404212/ https://www.ncbi.nlm.nih.gov/pubmed/34407417 http://dx.doi.org/10.1016/j.celrep.2021.109513 |
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