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On the roles of intrinsically disordered proteins and regions in cell communication and signaling

For proteins, the sequence → structure → function paradigm applies primarily to enzymes, transmembrane proteins, and signaling domains. This paradigm is not universal, but rather, in addition to structured proteins, intrinsically disordered proteins and regions (IDPs and IDRs) also carry out crucial...

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Detalles Bibliográficos
Autores principales: Bondos, Sarah E., Dunker, A. Keith, Uversky, Vladimir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404256/
https://www.ncbi.nlm.nih.gov/pubmed/34461937
http://dx.doi.org/10.1186/s12964-021-00774-3