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Brucella melitensis UGPase inhibits the activation of NF-κB by modulating the ubiquitination of NEMO
BACKGROUND: UTP-glucose-1-phosphoryl transferase (UGPase) catalyzes the synthesis of UDP-glucose, which is essential for generating the glycogen needed for the synthesis of bacterial lipopolysaccharide (LPS) and capsular polysaccharide, which play important roles in bacterial virulence. However, the...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404259/ https://www.ncbi.nlm.nih.gov/pubmed/34461896 http://dx.doi.org/10.1186/s12917-021-02993-9 |