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Identification of prognostic values defined by copy number variation, mRNA and protein expression of LANCL2 and EGFR in glioblastoma patients

BACKGROUND: Epidermal growth factor receptor (EGFR) and lanthionine synthetase C-like 2 (LanCL2) genes locate in the same amplicon, and co-amplification of EGFR and LANCL2 is frequent in glioblastoma. However, the prognostic value of LANCL2 and EGFR co-amplification, and their mRNA and protein expre...

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Detalles Bibliográficos
Autores principales: Zhao, Hua-fu, Zhou, Xiu-ming, Wang, Jing, Chen, Fan-fan, Wu, Chang-peng, Diao, Peng-yu, Cai, Lin-rong, Chen, Lei, Xu, Yan-wen, Liu, Jing, Li, Zong-yang, Liu, Wen-lan, Chen, Zhong-ping, Huang, Guo-dong, Li, Wei-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404333/
https://www.ncbi.nlm.nih.gov/pubmed/34461927
http://dx.doi.org/10.1186/s12967-021-02979-z