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Dynamics of epigenetic regulator gene BCOR mutation and response predictive value for hypomethylating agents in patients with myelodysplastic syndrome

BACKGROUND: BCOR (BCL6 corepressor) is an epigenetic regulator gene involved in the specification of cell differentiation and body structure development. Recurrent somatic BCOR mutations have been identified in myelodysplastic syndrome (MDS). However, the clinical impact of BCOR mutations on MDS pro...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Xu, Feng, Zhang, Zheng, Guo, Juan, He, Qi, Song, Lu-Xi, Wu, Dong, Zhou, Li-Yu, Su, Ji-Ying, Xiao, Chao, Chang, Chun-Kang, Wu, Ling-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404357/
https://www.ncbi.nlm.nih.gov/pubmed/34461985
http://dx.doi.org/10.1186/s13148-021-01157-8